This is the analysis of white matter using FSLs TBSS
Participants
Total number of scans = 120 (males and females)
Total scans used in analysis= 118
Excluded subs 329 and 372 from analyses due to bad behavior data and Subject 347 failed quality control check in DSI
Scan parameters
QSIprep
Version used: 0.16.0RC3
The following parameters were used
Preprocessing for FSL
The data needs to be reconstructed and prepared for FSL.
FSL TBSS
First, Let me plot and check all of our FA data
Let’s look at the distribution for maze accuracy behavior. Data appears to be not normally distributed.
## Warning: Removed 36 rows containing non-finite values (`stat_bin()`).
## Warning: Removed 36 rows containing non-finite values (`stat_bin()`).
Let’s just double check that by running a normality test.
The data is not normally distributed with p = 6.1641918^{-13}.
| ROI | p.value |
|---|---|
| Middle_cerebellar_peduncle | 0.0090485 |
| Splenium_of_corpus_callosum | 0.0018326 |
| Fornix_(column_and_body_of_fornix) | 0.0378160 |
| Inferior_cerebellar_peduncle_R | 0.0165339 |
| External_capsule_R | 0.0076241 |
| External_capsule_L | 0.0489276 |
| ROI | estimate | p.value | statistic | n | gp | Method |
|---|---|---|---|---|---|---|
| Middle_cerebellar_peduncle | -0.2484085 | 0.0262958 | -2.264876 | 82 | 2 | pearson |
| Medial_lemniscus_R | -0.2246881 | 0.0450978 | -2.036462 | 82 | 2 | pearson |
| Superior_fronto-occipital_fasciculus_(could_be_a_part_of_anterior_internal_capsule)_R | -0.2700141 | 0.0154250 | -2.476693 | 82 | 2 | pearson |
| Superior_fronto-occipital_fasciculus_(could_be_a_part_of_anterior_internal_capsule)_L | -0.2658221 | 0.0171622 | -2.435294 | 82 | 2 | pearson |
We want to know whether sex mediates the relationship between FA and Maze Accuracy in midlife adults. in this case X= ACC, Y = FA and M = sex. Looks like Sex does not mediate the effect of FA on ACC in middle cerebellar peduncle.
| ROI | estimate | p.value | statistic | n | gp | Method |
|---|---|---|---|---|---|---|